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The term heart disease (coronary heart disease) is a term that describes many heart disorders, including high blood pressure, coronary artery disease, and clogging of the arteries.
Any number of diseases related to the heart and blood vessels can come under the umbrella of heart disease. Grouped together these diseases are the leading cause of death in the Western world.
The term heart disease (coronary heart disease) is a term that describes many heart disorders, including high blood pressure, coronary artery disease, and clogging of the arteries.
Any number of diseases related to the heart and blood vessels can come under the umbrella of heart disease. Grouped together these diseases are the leading cause of death in the Western world.
The most common types of heart disease occur due to inadequate blood flow to the heart muscle.
NB: Obese people are at increased risk of due to their higher rates of hypercholesterolemia (high LDL cholesterol), diabetes and hypertension.
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Your heart is a living pump. It works to keep your blood moving and oxygenated. A network of blood vessels called coronary arteries supply blood and nutrients to your heart to keep it functioning in this way.
More about Description
Your heart is a living pump. It works to keep your blood moving and oxygenated. A network of blood vessels called coronary arteries supply blood and nutrients to your heart to keep it functioning in this way.

There are three main coronary arteries – right (RCA), left anterior descending (LAD) and left circumflex artery (CX).
Each of the coronary arteries branches into smaller arteries that reach all the areas of your heart muscle.
The heart pumps ‘used’ blood through the lung capillaries where waste gas (carbon dioxide) is expelled and fresh oxygen is taken up. This fresh oxygenated blood is bright red and is pumped through the aorta (the main artery of the heart) into the capillaries, where nutrient and oxygen exchange within cells takes place. It then returns to the heart through veins.
Heart failure, for whatever reason, can be fatal. The heart is one of the hardest working organs in the body. It contracts and expands around 100,000 times a day, it supplies 96,000 kilometres of blood vessels and pumps in excess of 10,000 litres of blood around the body each day. This constant action is stressful and makes this system particularly vulnerable to damage and disease.
Heart disease is any disorder that affects the heart's ability to function in this normal way.
Some heart diseases can be present at birth (congenital); others develop as we grow and may be dependant on factors like genetics, diet (nutrition), the environment and toxins; others may be degenerative (or medical).
Problems can arise in the heart muscle, valves, or surrounding arteries. The most common form of heart disease is a narrowing or blocking of the coronary arteries (atherosclerosis). Following are examples of terms used to describe heart disease, followed by brief explanations of the most common problems:
Cardiovascular disease involves the heart and its two networks of blood vessels, the system which circulates the blood throughout the body and the system which circulates the blood through the lungs.
Coronary artery diseases (CAD) are diseases of the arteries that supply the heart muscle with blood. CAD is one of the most common forms of heart disease and the leading cause of heart attacks. It generally comes from blood flow obstructions. The most common cause of such obstructions is a condition called atherosclerosis. Coronary artery disease can cause other heart problems, such as chest pain angina and heart attack (myocardial infarction).
Coronary heart disease is also known as ischemic heart disease and is similar to coronary artery disease but a broader term that refers to both diseases of the arteries and their resulting complications, (chest pain, heart attacks and scar tissue).
Cardiomyopathy is a condition that includes all diseases of the heart muscle. Types of cardiomyopathy include ischemic, which is caused by loss of heart muscle from a heart attack; dilated, which means the heart is enlarged; hypertrophic, which means the heart muscle is thickened; and idiopathic or dilated idopathic, which means an enlarged heart without a known cause.
To the left is a normal heart - It has a complex grouping of outer muscles that work together to pump blood through the body.
To the right is a weak, diseased heart - This is a heart with muscle disease. It looks larger than a healthy heart. A heart like this cannot pump blood properly.
Valvular heart disease is a disease of the heart valves, narrowing, leaking or improper closure.
Pericardial disease is a disease of the sac that encases the heart (pericardium). Fluid accumulation (pericardial effusion) and stiffness (constrictive pericarditis). These can occur alone or together.
Congenital heart diseases are forms of heart disease that develop before birth and affect the formation of the heart muscle or its chambers or valves. Some congenital heart defects may be apparent from the time of birth, while others may not be detected until later in life.
Heart failure is not a condition where the heart stops. It is a condition which describes the heart not being able to pump blood adequately to the body's organs and tissues. Vital organs don't get enough blood, and therefore oxygen, causing signs like shortness of breath, fluid retention and fatigue.
Blood vessels diseases
There are four types of blood vessels are:
Types of blood vessel disorders include:
Arteriosclerosis and atherosclerosis
Arteriosclerosis is a condition in which the walls of your arteries become thick and stiff. Restricting blood flow to organs and tissues.
Atherosclerosis is the most common form of arteriosclerosis, referring to hardening of the arteries caused by accumulation of fatty deposits (plaques), often calcified, develop on the inside of the arterial walls and eventually cause blockages which lead to cardiovascular disease.
When the arteries of the heart narrow, you may experience chest pain or a heart attack.
Atherosclerosis is the result of the body's attempt to ‘repair’ injuries to the inside of the arterial walls. These injuries come about because of weaknesses in the walls and their exposed stress from the constant pumping action of the heart. Stress is increased by high blood pressure (hypertension) and emotional trauma.
The prevention of heart disease, heart attacks and strokes is synonymous with the prevention of atherosclerosis.
High blood pressure
Hypertension is the excessive force of blood pumping through your blood vessels. It affects 1 in every 4 people.
It is important to remember that hypertension is not a condition. It is a symptom of an underlying problem. In societies that do not have high cardiovascular disease rates, high-fat diets and obesity, or stressful, fast modern lives, hypertension does not occur. It is a common symptom of underlying stress or body malfunction. If this cause is pinpointed and treated, the hypertension will naturally subside to normal levels.
Common underlying causes that bring about high blood pressure including lifestyle issues such as excess alcohol, caffeine, high salt intake, hormone therapies, stress, anxiety and lack of exercise, as well as conditions like diabetes, arteriosclerosis, high cholesterol, and many of the cardiac diseases listed here.
Although potentially life-threatening, because hypertension is a symptom of a condition it is very much preventable and curable. If left untreated, the symptom will of course worsen, putting undue pressure on the heart muscle and depleting blood vessel strength. After a period of time this will lead to serious cardiac disease such as stroke and heart failure.
Stroke
A stroke is a sudden loss of brain function. It occurs when blood flowing to the brain is interrupted (ischemia) or when blood vessels in the brain rupture (haemorrhage). Stroke can cause a number of neurological complications.
Aneurysm
An aneurysm is a bulge or weakness in the wall of an artery or vein. Aneurysms usually enlarge over time, and because of this they have the potential to rupture and cause life-threatening bleeding. Aneurysms can occur in arteries in any location in your body.
Peripheral arterial disease and claudication
Claudication is when you experience pain in your arms or legs during exercise, a symptom of peripheral arterial disease. It is a disorder in which the arteries supplying blood to your limbs become clogged or partially blocked. Pain or cramping is commonly the first sign.
Vasculitis
This refers to an inflammation of the blood vessels. Vasculitis can affect the arteries, veins or capillaries. The inflammation may impair general blood flow.
Venous incompetence
This is a condition in which blood flows the wrong way through your veins. Veins have tiny valves that are designed to promote blood flow in a forward direction, i.e. back to the heart. However, if you happen to be suffering from infection, inflammation, abnormal blood clotting, or even high-back pressure in pregnancy, the valves may become damaged, allowing blood to flow backward and ‘pool’ in your legs.
Venous imcompetence can lead to the development of such complications as prominent and painful varicose veins, skin changes, ulcers and swelling in your legs.
When venous incompetence occurs in your arms, you may experience pain and swelling in your arms and prominent veins may appear.
Venous thrombosis
This is the formation of a blood clot (thrombus) in a vein that may damage the vein or it’s valves. Clots that break off and travel in the bloodstream can lodge in the lungs, (pulmonary embolism). This type of clot may cause a stroke. Deep vein thrombosis is where a similar clot develops deep within a muscle.
Varicose veins
This is a condition in which your veins become twisted and enlarged. The veins are usually located on the backs of your calves or on the inside of your legs. When valves in your veins don't function properly, blood can accumulate in your legs, causing the veins to bulge and twist.
Lymphedema
This is an obstruction of the lymphatic vessels that causes an excessive build-up of fluid, resulting in swelling and pain.
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“Heart and blood vessel diseases kill more than 16 million people worldwide and account for 30% of total deaths each year.” (WHO) Cardiovascular diseases are the number one killer of both women and men.
More about Statistics
“Heart and blood vessel diseases kill more than 16 million people worldwide and account for 30% of total deaths each year.” (WHO) Cardiovascular diseases are the number one killer of both women and men.
US Facts
European Facts
Cardiovascular disease is very much a disease of Western civilization.
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Decades of research show that poor lifestyle choices, beginning in childhood, are the main causes of cardiovascular disease. Ongoing factors, such as poor diet, nutritional deficiency, lack of exercise, poor fluid intake and increased toxicity and stresses form a recipe for circulatory disaster.
All of the above are major risk factors. More specifically, high blood pressure - hypertension (itself a result of any/all of the above), tobacco use, increased intake of saturated fats, lack of essential antioxidants (excessive exposure to free radicals via pesticides, chlorinated water, air pollutants and other toxic chemicals, for example, is a strong risk factor for cardiovascular disease), elevated blood cholesterol, convenience lifestyle (i.e. reduced exercise) and genetic predisposition.
Decades of research show that poor lifestyle choices, beginning in childhood, are the main causes of cardiovascular disease. Ongoing factors, such as poor diet, nutritional deficiency, lack of exercise, poor fluid intake and increased toxicity and stresses form a recipe for circulatory disaster.
All of the above are major risk factors. More specifically, high blood pressure - hypertension (itself a result of any/all of the above), tobacco use, increased intake of saturated fats, lack of essential antioxidants (excessive exposure to free radicals via pesticides, chlorinated water, air pollutants and other toxic chemicals, for example, is a strong risk factor for cardiovascular disease), elevated blood cholesterol, convenience lifestyle (i.e. reduced exercise) and genetic predisposition.
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NB: Stress not only raises the blood pressure and constricts the arteries, it also generates large quantities of adrenalin which the body converts to adrenochrome - a potent free radical. |
The more ‘risk factors’ you have, the more likely you are to develop heart disease. All of these factors, bar genetic factors, can be changed and treated, even genetic risks can be modified with proper treatment.
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Blood pressure can vary with activity and age, but a healthy adult who is resting generally has a systolic pressure reading between 120 and 130 and a diastolic pressure reading between 80 and 90 (or below). |
Free radical activity plays a major role in the development and progression of atherosclerosis in particular, through oxidized lipoproteins and through direct attacks on the DNA of the arterial wall cells.
As the body attempts to repair damage to arterial walls, smooth-muscle cells (at the centre of the repair) themselves accumulate cholesterol and oxidized lipoproteins, and may begin to undergo calcification. As these deposits grow the inside opening of the artery begins to narrow, eventually create a blockage. If the blockage is in the coronary arteries angina pectoris may develop, or a heart attack may occur. If it is in the brain a stroke may occur, and if the blockage is in the legs intermittent claudication (pain or fatigue in arms and legs due to poor supply of oxygen to the muscles) may be experienced.
Iron has more recently been implicated in heart disease development. Researchers at Harvard University have concluded that it is not the overall iron intake that increases heart attack risks, but rather the specific intake of iron from red meats – potentially increasing your disease risk by up to 38%!
Cholesterol levels, and more specifically high LDL (low density lipoprotein) levels, are strong risk factors for cardiovascular disease, especially for men. Too much LDL cholesterol in the blood causes plaque to form on artery walls (the beginning of atherosclerosis). When this occurs arteries that supply blood to the heart get blocked (see description above) and you become at high risk of a heart attack. (See our Cholesterol section for more info)
Cholesterol is a soft, buttery substance. If the only build-up on the inside of the arteries were cholesterol, it would not get hard and the flow of blood would wash away the stuff. But, when that cholesterol gets mixed up with calcium the combination of the two becomes hard. That is why the honest term, used before the drug companies started fiddling with the facts, was 'hardening of the arteries'.
Homocysteine is an amino acid in the blood, high levels of which can significantly increase the risk of cardiovascular disease.
Mercury toxicity and Helicobacter pylori bacterium infection are potent initiators of coronary heart disease.
| Diabetes It is not often well understood that heart problems are actually a consequence (and symptom) of diabetes, and are the leading cause of death among diabetes sufferers, especially in adult-onset, or Type II diabetes. The American Heart Association estimates that 65% of patients with diabetes die of some form of cardiovascular disease. (See our Diabetes section for more info…)
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Obesity…Being overweight is, alongside diabetes, the leading cause of increased cholesterol levels, high blood pressure and coronary artery disease. Obesity increases your chances of developing all these risk factors in fact, as well as putting unnecessary strain on many other organs.
NB: Just from these short summaries you may be beginning to notice how all these conditions clearly interlink with one another…
Smoking, as well as increasing your risk of lung cancer, increases risks of heart disease and peripheral vascular disease. More than 400,000 deaths in the US alone occur each year because of the straining effects this habit has on the heart and blood vessels.
Research has shown that smoking increases the heart rate, tightens major arteries and can create irregularities in the timing of heartbeats, all of which make your heart work harder.
Although nicotine is the main active agent in cigarette smoke, other chemicals and compounds like tar and carbon monoxide are harmful to your heart too and lead to plaque build-up and injury to the vessel walls.
Inflammation…C-reactive protein (CRP) is a substance found in blood that is a marker for inflammation in the body. High levels of this protein are associated with an increased risk of heart disease and low levels with a low risk.
Studies suggest that CRP levels may even be a more important indicator of heart disease risk than high LDL cholesterol!
| In an eight-year study involving 27,939 women led by Paul Ridker, MD, director of the Center for Cardiovascular Disease Prevention at Brigham and Women's Hospital in Boston, more than half of the women who eventually developed heart disease had high CRP levels even though their LDL levels were not considered high. The New England Journal of Medicine November 2002 A Cleveland Clinic study found ultrasound evidence that clogged coronary arteries had not gotten worse among 502 patients who were most successful at lowering their CRP levels. The New England Journal of Medicine January 2005 A recent study at showed that as fitness levels go down, CRP levels go up. Johns Hopkins |
To help lower CRP levels it is recommended to concentrate on an anti-inflammatory diet, plus Omega 3 DHA fish oil supplements and anti-inflammatory and antioxidant supplement ingredients.
Finally, other indirect factors include…
Physical Inactivity - People who are inactive have a greater risk of disease leading to a heart attack. Exercise burns calories, helps to control cholesterol and diabetes, and may help to lower blood pressure. Exercise also strengthens the heart muscle itself and makes the arteries more flexible. Even moderate exercise is helpful if done regularly.
Genetics - Risk factors (high blood pressure, diabetes and obesity) may be passed from one generation to another…
Stress - We all deal with stress differently. How much and in what way stress affects us can vary from person to person. During times of stress the nervous system releases extra hormones (e.g. adrenaline). These hormones can raise blood pressure and injure the lining of the arteries. When the arteries heal the walls may harden or thicken, making is easier for plaque to build up.
Stress also increases the amount of blood clotting factors that circulate in your blood. Clots may block an artery already narrowed by plaque, resulting in a heart attack.
| Nutritional deficiency and toxicity It is never too late to begin improving heart health. By eliminating risk factors and properly managing your health, you can greatly reduce your risk of heart disease, and even begin to heal disease that is already present. Most people become vulnerable to these diseases because of a weakened immune system and systemic and organ-related weaknesses as a result of inadequate nutrition. This more often than not starts in early life, but continues to reduce health throughout life. Nutritional deficiencies, chemical and environmental toxicities are the major reason for the accentuation of most, if not all of the above risk factors. |
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Sadly, in most cases the first indication of cardiovascular disease is an actual acute heart event. This is because many of the underlying symptoms are either mistakenly considered a consequence of some other condition or disease, or they are simply misdiagnosed.
On most occasions symptoms are not noticed by the patient until such time that they cause a major condition….often being put down to another unrelated condition, being ‘run down’, or being under ‘stress’.
Sadly, in most cases the first indication of cardiovascular disease is an actual acute heart event. This is because many of the underlying symptoms are either mistakenly considered a consequence of some other condition or disease, or they are simply misdiagnosed.
On most occasions symptoms are not noticed by the patient until such time that they cause a major condition….often being put down to another unrelated condition, being ‘run down’, or being under ‘stress’.
Angina pectoris (chest pain) and stroke (cerebral infarction) are the most common physical symptoms that are first noticed.
If prior symptoms are realised, techniques and equipment can be used to confirm a diagnoses:
Electrocardiograms are tests particularly indicative for people with high risk factors (smoking, diabetes, obesity and hypertension). They can even show if a patient has already suffered a mild heart attack without noticing it.
Radioisotopes help to spot blood flow problems.
An Echocardiography is useful to evaluate the heart's performance.
Position emission tomography (PET scanning), CT scanning and magnetic resonance spectroscopy are also commonly used.
Surgery
Coronary arteriography is an invasive technique used to determine the extent and location of blockages in coronary arteries. It is only used prior to heart surgery such as angioplasty or bypass surgery.
As in all cases of potentially chronic illness, a thorough history - medical and genetic - should be taken, along with lifestyle, nutritional and dietary implications, and any other factors to help determine risk and current health statistics.
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As mentioned above, often symptoms are not noticeable until an actual stage of disease has already manifested.
Some symptoms associated with coronary artery disease may be more pronounced however. Such signs include:
Angina (chest pain) - This is the most common symptom, resulting from the heart intermittently not getting enough blood or oxygen. The intensity of the pain may vary from person to person.
As mentioned above, often symptoms are not noticeable until an actual stage of disease has already manifested.
Some symptoms associated with coronary artery disease may be more pronounced however. Such signs include:
Angina (chest pain) - This is the most common symptom, resulting from the heart intermittently not getting enough blood or oxygen. The intensity of the pain may vary from person to person.
Typical chest pain is felt under the sternum and is characterised by a heavy feeling, or a feeling of the chest being squeezed. Pain may also radiate to the shoulders, neck, or arms. It is often precipitated by exertion or emotional stress and is relieved by rest.
Women may also have a tendency to experience some areas of swelling - the ankles and legs for example – plus stomach upset, dizziness, rapid heartbeats, shortness of breath and chronic fatigue.
Shortness of breath – This can be a symptom of congestive heart failure (among many other things). The heart may be weak due to lack of blood and oxygen, resulting in shortness of breath accompanied by swollen feet and ankles too due to the reduced circulation.
When A Heart Attack is experienced you may experience intense chest pain that can be acute or last for a more extended period of time. There may be a sensation of pressure, burning, tightness, heaviness, or squeezing behind the breastbone. Pain in the left arm or jaw and of course laboured breathing also may occur. Alternatively pain may be more diffuse, spreading to the shoulders, neck, arms, abdomen and even back. Pain my come and go, feeling like a heaviness or burning sensation in the chest rather than intense pain.
Some victims of coronary heart disease experience none of these symptoms, while others experience them at varying levels. Initial emergency treatment is often recommended, such as the chewing of a regular strength adult Aspirin to inhibit blood clotting in the affecting coronary artery.
Stroke symptoms include a number of warning signs:
Symptoms may be especially noticeable on one particular side of the body.
Heart Failure symptoms may include:
Symptoms may continue for years unnoticed as the heart weakens.
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As is the case with most degenerative diseases there are two avenues of treatment - conventional (allopathic) and alternative (natural) treatment.
Conventional medicine employs surgery and drugs to treat the symptoms of cardiovascular disease.
As is the case with most degenerative diseases there are two avenues of treatment - conventional (allopathic) and alternative (natural) treatment.
Conventional medicine employs surgery and drugs to treat the symptoms of cardiovascular disease.
On the other hand, alternative methods concentrate on the whole body and underlying problem to bolster the body's natural healing powers and focus on removing the actual cause of the disease rather just treating the symptoms.
Conventional medicine helps to diagnose and treat acute, life-threatening events, but natural ‘wholistic’ methods are more gentle, have far fewer side effects and are capable of actually reversing heart disease and regaining full health as well as working to protect and prevent disease occurring in the first place.
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Lifestyle changes are of course the first line of prevention and treatment of cardiovascular disease.
Conventional medicine recommends medical interventions ranging from drugs to surgery. For example, a bypass operation may be performed to reduce a person's risk of a heart attack, or to try to help stop any further heart attacks from taking place. When this operation is performed a blood vessel from another body area is used to ‘re-route’ blood around the blocked artery.
Lifestyle changes are of course the first line of prevention and treatment of cardiovascular disease.
Conventional medicine recommends medical interventions ranging from drugs to surgery. For example, a bypass operation may be performed to reduce a person's risk of a heart attack, or to try to help stop any further heart attacks from taking place. When this operation is performed a blood vessel from another body area is used to ‘re-route’ blood around the blocked artery.
Many prescription medications are used every day to help prevent or control coronary heart disease (CHD). However, if medications are needed lifestyle changes still must be undertaken for results to take effect.
Common Drugs used to treat CHD include:
Aspirin helps to lower the risk of a heart attack for those who have already had one. It also helps to keep arteries open in those who have had a previous heart bypass or other procedure.
However, because of its side effects aspirin is not approved by the Food and Drug Administration in the US for preventing heart attacks in healthy individuals with careful assessment.
Some of the most common aspirin side effects are stomach pain, heartburn, nausea and vomiting. (An aspirin overdose or higher dosage than recommended can cause very serious health issues).
Long-term use of Aspirin has shown to cause gastrointestinal tract complications, including micro-bleeding and ulcers. There is also a risk of haemorrhagic stroke.
ACE (angiotensin converting enzyme) inhibitors stop the production of a chemical that makes blood vessels narrow and is used to help control high blood pressure and help heal damaged heart muscle. It may be prescribed after a heart attack to help the heart pump more efficiently. It is also used for heart failure cases.
Side effects may include a dry cough, headache and dizziness. ACE inhibitors may also cause elevated amounts of potassium. More rare side effects can include skin rashes, kidney problems, and swelling of the face, lips and throat
Example drugs: Benazepril (Lotensin), Captopril (Capoten), Enalapril (Vasotec), Fosinopril (Monopril), Lisinopril (Prinivil, Zestril), Moexipril (Univasc), Perindopril (Aceon), Quinapril (Accupril), Ramipril (Altace), Trandolapril (Mavik).
News
Many heart disease patients who are already receiving state-of-the-art therapy do not benefit from additional treatment with angiotensin converting enzyme (ACE) inhibitors, according to results of a new study funded by the National Heart, Lung, and Blood Institute (NHLBI), part of the National Institutes of Health. The study provides the most definitive evidence to date of the effect of the drug in stable heart disease patients. Researchers found that ACE inhibitors do not lower the risk of cardiovascular death, heart attack, or the need for coronary revascularization (bypass surgery or angioplasty to restore blood flow to clogged arteries).
New Orleans, LA, Nov. 7, 2004
http://www.nhlbi.nih.gov/new/press/04-11-08a.htm
Angiotensin II Receptor Blockers
Angiotensin II constricts blood vessels and causes the kidneys to retain more fluid. The main function is to increase blood pressure. Angiotensin II receptor blockers (ARBs) inhibit the effects of angiotensin II by blocking the receptor, thereby reducing constriction and helping to reduce blood pressure.
ARBs also help to minimize over-exertion of the heart muscle and help prevent progression to heart failure. ARBs are mainly used when ACE inhibitors are not tolerated by the individual.
Side effects may include headache, lightheadedness, nasal congestion, back and leg pain, diarrhea, rash, indigestion and insomnia. More rare side effects may include kidney failure, liver failure, allergic reaction, reduced white blood cell count and swelling of tissues (angioedema).
Because ARBs can cause birth defects they are not recommended if pregnant or planning to become pregnant.
Example drugs: Candesartan (Atacand), Eprosartan (Teveten), Irbesartan (Avapro), Losartan (Cozaar), Olmesartan (Benicar), Telmisartan (Micardis), Valsartan (Diovan).
News
Do angiotensin II receptor blockers increase MI risk, or do they not?
A pair of articles in ‘Circulation’ magazine/journal discusses the controversy over whether or not angiotensin-II-receptor blockers (ARB) result in a paradoxical increase in risk of myocardial infarction (MI), despite reducing blood pressure. (Also raised, in a BMJ editorial in 2004.)
Suggesting that these drugs do increase the risk of MI argue firstly that in general, clinical trials with ARB have not shown the reduction in MI risk that could have been expected given the drop in blood pressure that they achieve. They discuss the major trials involving ARB, and also the various (and discordant) meta-analyses that have been carried out….
http://www.nelm.nhs.uk/Record Viewing/viewRecord.aspx?id=569354
Antiplatelets
Blood clots can block blood flow to the heart or brain, causing a heart attack or stroke. Antiplatelet medications work by preventing platelets from sticking together to form blood clots to reduce the risk of a heart attack or stroke occurring, specifically in people who have already had a heart attack or stroke, or who have poor circulation that causes pain.
Possible side effects include allergic reaction (sneezing, respiratory congestion, swelling of throat, restricted breathing, itching or skin rashes), nausea, indigestion or stomach pain,
unusual bleeding or bruising, ringing in ears (tinnitus), bloody urine, convulsions or seizures (rare).
Example drugs: Clopidogrel (Plavix), Ticlopidine (Ticlid).
Beta blockers slow the heart and make it beat with less force, so blood pressure drops and the heart works less hard. It is used for high blood pressure, chest pain and to prevent a repeat heart attack.
The most common side effects are cold hands and feet, tiredness and sleep disturbance (nightmares). Less common side effects include, impotence, dizziness, wheezing, digestive tract problems, skin rashes and dry eyes.
Example drugs: Acebutolol (Sectral), Atenolol (Tenormin), Atenolol Injection (Tenormin Injection), Bisoprolol (Zebeta), Carteolol (Cartrol), Metoprolol ER (Toprol XL), Metoprolol Oral (Lopressor), Nadolol (Corgard), Pindolol (Visken), Propranolol (Inderal), Propranolol ER (Betachron ER, Inderal LA, Innopran XL), Timolol Oral (Blocadren).
News
Guidelines issued by the NHS drugs watchdog have given new advice on which medicines should be used to treat high blood pressure. They recommend that beta-blockers should no longer be routinely used, expect in special situations….
There is also increasing evidence that the most frequently used beta-blockers can carry a higher risk, some studies suggest up to 30% higher, of provoking type 2 diabetes than the new drugs. Many of the new medicines also have fewer side effects than beta-blockers.
http://news.bbc.co.uk/1/hi/health/5124382.stm
Nitrates (including nitroglycerine) – relax blood vessels and stop chest pain.
Side effects include a feeling of pulsating fullness in the head (most common side effect) or a headache, a drop in blood pressure, which can cause dizziness or a burning sensation under the tongue.
Example drugs: Isosorbide Dinitrate, Sublingual and Chewable (Isordil, Sorbitrate), Isosorbide Mononitrate (Imdur, Ismo, Isotrate ER, Monoket), Nitroglycerin ER (Nitroglyn),
Nitroglycerin Ointment (Nitro-Bid Ointment, Nitrol), Nitroglycerin Skin Patches (Deponit, Minitran, Nitro-Dur, Nitrodisc, Transderm-Nitro), Nitroglycerin Spray (Nitrolingual).
Calcium channel blockers – relax blood vessels and are used for high blood pressure and chest pain.
Side effects can include drowsiness, increased appetite, weight gain, breathing difficulties (shortness of breath, coughing, or wheezing), irregular or slow heartbeat, allergic reactions (skin rash or hair loss), constipation, tenderness or bleeding of the gums, swelling of feet, ankles and legs, and fainting.
Example drugs: Amlodipine (Norvasc), Bepridil (Vascor), Diltiazem ER (Cardizem CD, Cardizem LA, Cardizem SR, Cartia XT, Dilacor XR, Diltia XT, Taztia XT, Tiamate, Tiazac), Felodipine (Plendil), Isradipine (DynaCirc), Nicardipine (Cardene), Nicardipine SR (Cardene SR), Nifedipine ER (Adalat CC, Afeditab CR, Nifediac CC, Procardia XL), Nisoldipine (Sular), Verapamil (Calan, Isoptin), Verapamil Extended-release (Calan SR, Covera-HS, Isoptin SR, Verelan, Verelan PM).
Oral Anticoagulants - these are like antiplatelets, but work to dissolve blood clots that have already formed. By dissolving the blood clots anticoagulants can lower the risk for heart attack and stroke.
Side effects may include bleeding from gums, nosebleeds, pinpoint skin spots, heavier bleeding, cough or hoarseness, fever or chills, lower back or side pain, painful or difficult urination, skin rash, hives and itching, blisters, blue or purple toes, ulcers, or white spots in mouth or throat, swelling of face, feet, or lower legs and yellow eyes or skin.
Example drugs: Warfarin (Coumadin, Jantoven), Hepalin injection.
Salicylates - reduce pain and swelling by blocking the body's production of chemicals that cause inflammation.
Salicylates (see Aspirin above) are also used to help prevent platelets from sticking together to form blood clots. These medications can reduce the risk of heart attack or stroke, specifically in people with poor circulation.
Side effects can include bloody stools, bloody or cloudy urine, fever, chills, pain in lower back, skin rash, hives, itching, ulcers, white spots on lips or in mouth, sore throat, stuffy nose, swelling of face or extremities, unusual bleeding or bruising, tiredness or weakness, vomiting, weight gain, yellow eyes or skin, heartburn or indigestion nausea, vomiting, or stomach pain, drowsiness, trouble sleeping, nervousness or jitters.
Example drugs: Aspirin Gum.
Diuretics (‘water pills’) - decrease fluid in the body and are used for high blood pressure.
Side effects may include black stools, blood in urine, cough or hoarseness, fever or chills, joint pain, lower back or side pain, pinpoint red skin spots, skin rash or hives, stomach pain, nausea and vomiting and yellow eyes or skin.
Diuretics can also be associated with potassium and/or sodium loss…
Signs of potassium loss can include dryness of mouth, increased thirst, irregular heartbeat, mood changes, muscle cramps or pain, nausea or vomiting, unusual tiredness or weakness and a weak pulse.
Signs of sodium loss can include confusion, convulsions, decreased mental activity, irritability, muscle cramps and unusual tiredness or weakness.
Blood cholesterol-lowering agents - decrease LDL cholesterol levels in the blood.
Side effects include soreness, aches, pain, weakness, fatigue, difficulty walking or getting out of bed. Also many reports exist on the use of Statin drugs and muscle or nerve damage.
News
High Doses of Statins Carry Dangers, Swedish Report Says (press release)
July 14, 2006
The American National Cholesterol Education Program said last year that people at high risk of heart disease should be treated more aggressively. Aggressively lowering cholesterol means that LDL cholesterol should be lowered to less than 1.81 millimoles per liter of blood (mmol/l) in high-risk individuals. Current guidelines generally recommend 2.56 mmol/l.
According to Uffe Ravnskov, an independent researcher from Lund, Sweden, achieving this new goal would mean that most of the western world's adult population would be on statins, and doses would have to be more than eight times higher than currently used.
Doses this high would increase both the number and seriousness of side effects, Ravnskov's team contended. Side effects could include heart failure, myalgia and rhabdomyolysis (which destroys muscle tissue), neurological problems and cancers.
In addition, the researchers claimed that clinical trials suggest that higher doses of statins do not lower overall mortality, and side effects are generally under-reported.
(http://www.newstarget.com)
Thrombolytic agents - also called ‘clot busting drugs’, given during a heart attack to break up a blood clot in a coronary artery in order to restore blood flow.
Side effects may include bleeding from cuts, gums, or wounds, fever, low blood pressure, agitation, bloating, blue or purple toes, blurred vision, bruising, changes in facial skin, chest discomfort, chills, confusion, decreased urine output, depression, dizziness, irregular breathing, skin flushing, headache, indigestion, lethargy, muscle cramps or spasms, twitching, nervousness, numbness, pounding in the ears, rapid weight gain, shortness of breath, sweating, swelling of eyes, face, lips, or tongue, unusual tiredness or weakness, vomiting, weakness in arms or legs, and yellow eyes or skin.
Example drugs: Alteplase (Activase), Anistreplase (Eminase), Reteplase (Retavase),
Streptokinase (Streptase), Tenecteplase (TNKase), Urokinase (Abbokinase).
Glycoprotein IIb/IIIa Inhibitors - these are antiplatelet medications that work by preventing the blood from clotting during chest pain or a heart attack, or when undergoing surgical or procedural treatment.
Side effects may include bleeding, stomach, intestines, or other internal organs, increased bruising, stomach irritation and allergic reaction.
Example drugs: Abciximab Injection (ReoPro), Eptifibatide (Integrilin), Tirofiban (Aggrastat).
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Whereas conventional drugs aim to suppress and stem symptoms, the natural approach aims at containing and even reversing the underlying causes of cardiovascular disease, such as the beginning of atherosclerosis. Nutritional supplements and dietary interventions are generally based on the principles that aim at preventative measures too.
Diet and lifestyle changes and correct nutritional supplementation are categorically the most important tools in the natural treatment of cardiovascular disease.
More about Natural Treatments
Whereas conventional drugs aim to suppress and stem symptoms, the natural approach aims at containing and even reversing the underlying causes of cardiovascular disease, such as the beginning of atherosclerosis. Nutritional supplements and dietary interventions are generally based on the principles that aim at preventative measures too.
Diet and lifestyle changes and correct nutritional supplementation are categorically the most important tools in the natural treatment of cardiovascular disease.
For example…atherosclerosis can be prevented by developing strong artery walls, by controlling the factors that cause injuries to them and by minimizing the level of fats, lipoproteins, cholesterol and homocysteine build up. All of these areas can be potentially controlled and reversed by nutritional and supplementation methods, where the following ingredients may benefit.
| Betaine HCL | Betaine hydrochloride is obtained from an alkaloid that plays an important role in the health of the cardiovascular system and the liver. Studies have suggested that Betaine helps to reduce potentially toxic levels of homocysteine (a naturally occurring amino acid that can be harmful to blood vessels and can contribute to the development of health problems associated with poor heart function). Betaine helps the body extract minerals from foods through the digestive process, and without enough stomach acid, mineral depletion can result, leading to a variety of ailments. Betaine functions synergistically with S-adenosylmethionine (SAM-e), folic acid and vitamins B6 and B12, to break down homocysteine. |
| L-Arginine HCL | The body also uses arginine to make nitric oxide (NO), a substance that relaxes blood vessels and so has been proposed as a treatment for various cardiovascular diseases, including congestive heart failure. In studies Arginine has shown potential benefit for use after a heart attack to aid recovery. People with advanced hardening of the arteries, or atherosclerosis, often have difficulty walking due to lack of blood flow to the legs (intermittent claudication). Significant doses of Arginine have proven in studies to improve this condition. Studies with angina have also found that treatment with Arginine can improve exercise tolerance. |
| L-Proline |
L-Proline and L-Lysine are two natural amino acids that show promise in helping to prevent fatty deposits in blood vessels. Researchers have recently identified a particle associated with LDL cholesterol which is believed to cause plaque development. L-Proline and L-Lysine tend to form a barrier-like layer around the particle, helping to push it away from blood vessel walls. |
| N-Acetyl L-Cysteine | NAC is a more stable, more bioavailable form of the amino acid cysteine that acts as an antioxidant and a precursor to glutathione (GSH), a critical antioxidant. NAC can stimulate GSH synthesis, enhance glutathione-s-transferase activity, promote detoxification and act as an antioxidant. These benefits have clinical applications in heart disease treatment and prevention. NAC inhibits heart damage by preventing LDL cholesterol from being oxidized, by reducing plasma homocysteine levels and by free-radical quenching effects. NAC protects against ischaemic and reperfusion damage. It also potentiates the coronary dilating and anti-platelet effects of nitroglycerine. |
| Bromelain | Bromelain may help breakdown amyloid deposits (amyloid is a protein-like substance that can build up and cause damage to many organs in the body such as the kidneys, liver, or heart). Bromelain inhibits the aggregation (clumping) of platelets, and so it has shown to be of good benefit in helping to prevent heart disease caused by plaque formation. |
| Ginkgo biloba | Ginkgo flavone glycosides (primarily quercetin, kaempferol, and isorhamnetin) are responsible for its antioxidant activity and may help to inhibit platelet aggregation. These two actions may help prevent circulatory diseases, such as atherosclerosis, and support the brain and central nervous system. Laboratory studies have shown that Ginkgo may improve blood circulation by dilating blood vessels. |
| Grape Seed extract | Grape Seed Extract which is high in Oligomeric Proanthocyanidins (OPC’s or PCO’s) is powerful antioxidant that can reduce the damage done by free radicals, strengthen and repair connective tissue, and promote enzyme activity. PCO extracts have been scientifically studied to enhance capillary strength and vascular function and enhance immune resistance. PCO has been shown to be 50 times more potent than vitamin E in helping to prevent the stickiness of blood platelets that can lead to blood clots and strokes. |
| Green Tea | Green Tea contributes towards heart health through its role as gentle stimulant to the heart and circulatory system, by helping to strengthen and keep blood vessel walls soft, by the action of phenols inhibiting the absorption of cholesterol in the digestive tract, and by decreasing the blood's tendency to form clots. |
| Hawthorne Berry | Hawthorn berries are one of the most valuable medicinal herbs used in the treatment of congestive heart failure and circulatory disorders for many years. They help to increase blood flow to the heart and brain, protects the heart from irregular beats, enhances the strength of the heart's contractions and mildly lowers blood pressure. Compounds in hawthorn also help to protect the heart against oxygen deprivation, a condition that often leads to angina, a disease marked by intense chest pain. Hawthorn is rich in bioflavonoids, which relax and dilate the arteries. These compounds are powerful antioxidants that help increase the flow of blood and oxygen to the heart. The bioflavonoids give strength to the walls of blood vessels and improve blood flow. Components in hawthorn have also been shown to lower cholesterol, and the amount of plaque in arteries. |
| Policosanol | Policosanol contains naturally occurring compounds extracted from the waxy coating of the stems and leaves of sugar cane. Clinical trials have proven that Policosanol can reduce total cholesterol levels, reduce LDLcholesterol levels and increase HDL cholesterol, reduce LDL /HDL cholesterol ratios. Policosanol also helps to inhibit platelet aggregation. |
| Iron (Reduced) | Iron is necessary for the production of hemoglobin. The function and synthesis of hemoglobin, which carries most of the oxygen in the blood, is dependent on iron. Iron-deficiency can lead to decreased production of hemoglobin and a microcytic, hypochromic anemia. Iron is an essential trace mineral in human nutrition. It is involved in the entire process of respiration, including oxygen transport and electron transport. Iron overload disorders can lead to coronary heart disease and congestive heart failure, among other things. |
| Magnesium ascorbate | Research indicates magnesium deficiency to potentially be a factor in the development of atherosclerosis and coronary artery disease. Several clinical studies indicate that maintenance of adequate red blood cell magnesium levels may be key in fighting these problems. |
| Alpha Lipoic Acid | Vitamin E and alpha-lipoic acid are potent antioxidants with the potential to preventing blood vessel cell death. |
| Butchers broom | The steroidal saponins contained within Butcher’s broom are thought to be responsible for the medicinal actions. These constituents are reported to improve the strength and tone of the veins and act as mild diuretics for detoxification. They may also lead to constriction of the veins, which helps blood return from the extremities. Butcher's broom extracts also exert a mild anti-inflammatory effect. Chemicals in butcher's broom attach to and strengthen certain parts of blood vessels. As a result, butcher's broom tightens blood vessels, which helps to keep blood circulating throughout the body. It also acts to improve the flexibility of blood vessel walls. |
| Hesperidin | In trials Hesperidin has reduced blood pressure values and protected the heart from damage by increasing folate levels and reducing homeocysteine concentrations. It has been recommended for use in the treatment of vascular disorders like hypertension, and to support capillary health and combat varicose veins. |
| Rutin and Quercetin | Rutin is a supplement used to treat poor blood circulation, hemorrhoids, and Meniere’s disease. It may also be used to treat varicose veins or skin bruising. Quercetin is a flavonoid that occurs in plants as glycosides, such as rutin (quercetin rutinoside) in tea. Quercetin and Rutin are used for blood vessel protection. Rutin inhibits platelet aggregation, making the blood thinner and improve circulation. It also has strong antioxidant properties. It is important because it strengthens capillaries and can help people who bruise or bleed easily. |
| SAMe | People with liver or heart disease, or Alzheimer's disease have been shown to have low levels of SAMe in the blood. People who are concerned about heart or artery disease due to elevated blood levels of homocysteine (HCy) can note SAMe as beneficial. SAMe helps to transport toxic levels to the detoxifiers cysteine, N-Acetylcysteine, glutathione and taurine. |
| Glutathione | The endothelial cells that line the blood vessels are arranged in a single, attenuated layer, and are vulnerable to oxidative challenge. They are continually exposed to oxidants that reach the circulation. Atherosclerosis appears linked to oxidative damage to the vessel wall, for example. Oxidative stress within atherosclerotic arteries depletes Glutathione and other antioxidants causing inflammation. Glutathione can produce coronary vasodilatation by normalizing prostaglandin synthesis. Reduced levels of Glutathione have been found in the platelets of patients with acute myocardial infarction. |
| Folic acid | Folic acid deficiency has been clearly linked to an elevated level of homocysteine (in turn linked to cardiovascular disease). Folic acid has been shown to effectively lower levels of an amino acid in the blood called homocysteine. “By increasing folic acid intake and thus decreasing homocysteine, the researchers say the risk of heart disease would drop by 16%, blood clots in the legs by 25%, and stroke by 24%.” (BMJ) |
| Choline bitartrate | Choline Bitartrate prevents fats from accumulating in liver. Deficiency symptoms include fatty deposits in the liver, high blood pressure and cirrhosis. Choline aids in emulsifying cholesterol so it doesn't settle on the arterial walls. Choline helps to build cell membranes and move fats and nutrients between cells. It is used to help increase good, and reduces bad cholesterol. |
| Vitamin B6 | Low dietary intake of vitamin B6 is associated with higher risk of having heart disease due to the fact that vitamin B6, together with vitamin B9 (folic acid) and vitamin B12, help to keep homocysteine levels under control. |
| Vitamin C | Vitamin C's connection with lipoprotein-a, a substance whose levels in the blood have been linked to cardiovascular disease, have promoted its necessity in helping to prevent heart conditions. Lipoprotein-a is also a major component of arterial plaque. Vitamin C therefore serves to strengthen blood vessel walls. |
| Vitamin B12 | Evidence suggests that folic acid and vitamin B12 work together to protect the heart against cardiovascular disease, helping to also inhibit homocysteine levels. Vitamin B12 also helps to support the nerve cells. |
| Xtend-Life Cardio Klenz Cardio Klenz is a completely unique formulation of ingredients to cover every aspect of heart health, protection and disease rectification, aiding the function of not only the heart, but all surrounding vessels, related organs and the blood itself. It also aims to protect against and reduce other diseases relating to cardiovascular disease, such as obesity, cholesterol imbalance and diabetes. It is the only true all-round heart formula available with such bioavailability and efficacy, at an affordable price. |
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Here you will find 3 recommended protocols for heart and artery health.
Protocol 1 – Maintenance
As part of a maintenance program we recommend Xtend-Life Cardio-Klenz combined with our Total Balance and Omega 3/DHA Fish Oil Esters as an excellent step towards overall heart health protection:
| Product | Quantity Per Day | You need |
| Xtend-Life Cardio-Klenz | 4 tablets per day (2 X 2) | 1 bottle per month |
| Xtend-Life Total Balance | 6 tablets per day (2 X 3) | 2 bottles per month |
| Omega 3/DHA Esters | 2 soft gels per day | 1 bottle per month |
Protocol 2 – Intensive Use
Xtend-Life Cardio-Klenz at a higher dose, combined with Total Balance and Omega 3/DHA Fish Oil Esters are recommended for a more proactive for people at higher risk, or who currently suffer a related medical problem:
Product
Quantity Per Day
You need
Xtend-Life Cardio-Klenz
8 tablets per day
2 bottles per month
Xtend-Life Total Balance
6 tablets per day (2 X 3)
2 bottles per month
Omega 3/DHA Esters
2 soft gels per day
1 bottle per month
NB: Cholest-Natural can also be added to this regime, if you wish to help reduce/protect against cholesterol damage also.
Protocol 3 – High Cholesterol
Xtend-Life Cardio-Klenz combined with our Total Balance and Omega 3/DHA Fish Oil Esters, and Xtend-Life Cholest-Natural as a beneficial regime for heart health AND cholesterol balance:
| Product | Quantity Per Day | You need |
| Xtend-Life Cardio-Klenz | 4 tablets per day (2 X 2) | 1 bottle per month |
| Xtend-Life Total Balance | 6 tablets per day (2 X 3) | 2 bottles per month |
| Omega 3/DHA Esters | 2 soft gels per day | 1 bottle per month |
| Xtend-Life Cholest-Natural | 2 soft gels per day | 1 bottle per month |
NB: Please note that we develop our formulas in a way that minimizes possibilities of interaction. However, as with all natural supplements there is still potential for ingredients to interact with prescription drugs. You are advised to either check with your physician or Contact Us with details of your medicines so that we can check our databases for potential problems.
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